TY  - JOUR
T1  - An Overview of Henoch Schonlein Purpura Diagnosis and Management Approach: Literature Review
A1  - Lama H. Ayoub
A1  - Hawazin H. Algubsani
A1  - Hassan A. H. Alsaihati
A1  - Nojoud F. Alnahdi
A1  - Naqa A. Sulis
A1  - Atheer S. Alsaadi
A1  - Tahani N. Khalofi
A1  - Somaya A. A. Khammash
A1  - Saud F. Aljuraysi
A1  - Hanadi N. Abu Jabr
A1  - Hend A. Alshumiesy
JF  - International Journal of Pharmaceutical Research and Allied Sciences
JO  - Int J Pharm Res Allied Sci
SN  - 2277-3657
Y1  - 2021
VL  - 10
IS  - 1
DO  - 10.51847/t8m5D1d
SP  - 55
EP  - 59
N2  - Henoch-Schönlein purpura (HSP) is a systemic autoimmune disease of childhood mainly, but can also be seen in adolescence and adults. It is considered the most common vasculitis in the pediatric group. Recently, it has been termed IgA vasculitis due to the presence of immunoglobulin A in these patients. Eventually, patients develop a generalized vasculopathy in multiple areas, including skin, and other systems such as the gastrointestinal, urinary, and pulmonary systems can be affected. Rarely, more severe involvement of the central nervous system and lungs can happen. We aimed to review the literature reviewing the pathophysiology of Henoch-Schönlein purpura, along with its clinical features, diagnosis, and management. PubMed database was used for article selection. Papers were selected, obtained, and reviewed based on our inclusion and exclusion criteria. Henoch Schonlein Purpura is the most common vasculitis in the pediatric population, which reflects the heavy burden it causes on the health care system and the patients themselves. As a result, pediatricians must have a complete understanding of this disease to approach this disease properly. Managing this disease, focuses on supportive care and subsiding the inflammatory status with corticosteroid in some cases. Early diagnosis and treatment are pivotal to avoid possible complications and the need for surgery in some severe presentations.  
UR  - https://ijpras.com/article/an-overview-of-henoch-schonlein-purpura-diagnosis-and-management-approach
ER  -