TY  - JOUR
T1  - Association between Vitamin D Status and Type 1 Diabetes Mellitus in Saudi ‎Adolescents
A1  - Alqudsi K.K.
A1  - Abdelaziz S.A.
A1  - Al-Agha A.E.‎
JF  - International Journal of Pharmaceutical Research and Allied Sciences
JO  - Int J Pharm Res Allied Sci
SN  - 2277-3657
Y1  - 2019
VL  - 8
IS  - 3
SP  - 204
EP  - 211
N2  - Background: Nowadays, the deficiency of vitamin D (VD) is a health problem worldwide, that affects many people including adolescents who have type 1 diabetes mellitus (T1DM). However, the role of VD in autoimmune diseases such as T1DM has been a recent interest. Aim: This study was designed to assess the VD deficiency prevalence in Saudi adolescents with or without T1DM. Methods: In this case-control study, 49 T1DM and 49 control (non-DM) (N=98), age and gender-matched were enrolled. The study was carried out from May to September 2017 at King Abdulaziz University Hospital (KAUH). After obtaining the consent form, the blood samples were withdrawn to determine fasting blood glucose (FBG) and glycosylated hemoglobin (HbA1c) in blood and VD (25OHD) in serum. Statistical analysis was made by SPSS version 22. Results: Data showed that 25OHD levels were significantly lower in adolescents with T1DM compared to the controls (49.5 ± 26.9 nmol/L vs 67.96 ± 30.03 nmol/L). In the T1DM adolescents, VD was deficient in 44.9%, insufficient in 36.7%, and sufficient in 18.4% as compared with 34.7% (deficient), 26.5% (insufficient), and 42.86% (sufficient) in non-DM adolescents. Overall, VD was deficient and insufficient in 81.6% of the T1DM adolescents and 61.2% of non-DM adolescents, respectively. Considering sex, females showed higher significance between T1DM and non-DM groups in overall groups, and in all VD level subgroups, males showed significance (p
UR  - https://ijpras.com/article/association-between-vitamin-d-status-and-type-1-diabetes-mellitus-in-saudi-adolescents
ER  -