%0 Journal Article %T Efficacy and Safety of Sacubitril/valsartan in Patients with Heart Failure %A Waleed Alhabeeb %A Fakhr AlAyoubi %A Ahmad Hayajneh %A Fayez Elshaer %J International Journal of Pharmaceutical Research and Allied Sciences %@ 2277-3657 %D 2020 %V 9 %N 4 %P 11-18 %X Objective: Clinical trial data on sacubitril/valsartan are important. Considering that real-world data have important clinical implications, we aimed to report the efficacy and safety of sacubitril/valsartan in patients with heart failure (HF) in Saudi Arabia.Methods: This was a pilot prospective clinical trial consisting of adult patients (≥18 years old) with HF (left ventricular ejection fraction [EF] ≤40%) who were taking angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers for at least 1 month before presenting to the clinic and who were eligible for sacubitril/valsartan. Results: A total of 20 patients with a mean age of 60.75 years (range, 33–81 years) were included. At presentation, the majority of the patients presented with New York Heart Association (NYHA) class II symptoms (15/20), EF %U https://ijpras.com/article/efficacy-and-safety-of-sacubitrilvalsartan-in-patients-with-heart-failure