TY - JOUR T1 - Efficacy and Safety of Sacubitril/valsartan in Patients with Heart Failure A1 - Waleed Alhabeeb A1 - Fakhr AlAyoubi A1 - Ahmad Hayajneh A1 - Fayez Elshaer JF - International Journal of Pharmaceutical Research and Allied Sciences JO - Int J Pharm Res Allied Sci SN - 2277-3657 Y1 - 2020 VL - 9 IS - 4 SP - 11 EP - 18 N2 - Objective: Clinical trial data on sacubitril/valsartan are important. Considering that real-world data have important clinical implications, we aimed to report the efficacy and safety of sacubitril/valsartan in patients with heart failure (HF) in Saudi Arabia.Methods: This was a pilot prospective clinical trial consisting of adult patients (≥18 years old) with HF (left ventricular ejection fraction [EF] ≤40%) who were taking angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers for at least 1 month before presenting to the clinic and who were eligible for sacubitril/valsartan. Results: A total of 20 patients with a mean age of 60.75 years (range, 33–81 years) were included. At presentation, the majority of the patients presented with New York Heart Association (NYHA) class II symptoms (15/20), EF UR - https://ijpras.com/article/efficacy-and-safety-of-sacubitrilvalsartan-in-patients-with-heart-failure ER -