TY  - JOUR
T1  - The Role of Total Disc Replacement in Degenerative Disc Degeneration, Literature Review
A1  - Wafaa Sulaiman Alhifzi
A1  - Fahad Mohammed Alqahtani
A1  - Wael Abdulrahman Al Luhayb
A1  - Abdulaziz Musallam S Aljohani
A1  - Mohanad Misfer S Alkhathami
A1  - Jamal Abdulghani Taj
A1  - Shahd Mohammed Alanzan
A1  - Marwan Salah Alsaadi
A1  - Abdullah Ahmed Amin
A1  - Safar Dhawi Saleh Alyami
A1  - Abdullah Matuq Alaithan
JF  - International Journal of Pharmaceutical Research and Allied Sciences
JO  - Int J Pharm Res Allied Sci
SN  - 2277-3657
Y1  - 2021
VL  - 10
IS  - 1
DO  - 10.51847/hoJAYXW0H5
SP  - 127
EP  - 135
N2  - Degenerative disc degeneration (DDD) alludes to the progressive collapse of the disc to execute its function, resulting in a diminished range of motion and back inconvenience. Even though it is debilitating, the majority of people see their symptoms slowly go away without the requisite for surgery. However, numerous cases require surgical intercession, and spinal integration has been considered the gold standard for DDD in the past years. Nevertheless, spinal integration has shown to be related to a few complications. Subsequently, total disc restoration (TDR) surgery recently has been replacing spinal integration within the therapy of DDD. To review the role of TDR in DDD cases and provide a competent survey that covers the main aspects of this topic.

PubMed database was utilized for articles selection, and the following keys were utilized within the mesh ((“degenerative disc degeneration"[Mesh]) AND (“surgical management”[Mesh]) OR (“total disc replacement"[Mesh])). TDR works by mimicking the biomechanical function of an unscathed intervertebral disc, conserving physiological versatility and perhaps lowering the risk of adjacent segment degeneration as compared to lumbar fusion. 
UR  - https://ijpras.com/article/the-role-of-total-disc-replacement-in-degenerative-disc-degeneration-literature-review-vuuelj6jpb0zyml
ER  -