TY - JOUR T1 - Vitamin D and Multiple Sclerosis; Is There a Real Association? A1 - Mustafa Mohammed Al Brahim A1 - Omar Muhammed Aldosari A1 - Saeed Ali Saeed Alyahya A1 - Faisal Saeed Mohammad Alahmari A1 - Laila Zawan Ali Almalki A1 - Abdulaziz Muqbil Faleh Alshammari A1 - Ahmed Khalifah Albahrani A1 - Tahani Abduljalil Albahrani A1 - Saad Zaid Aljabr A1 - Faleh Mansour Alrashdi A1 - Shahad Ghurmullah Alghamdi A1 - Mohannad abdulrahman D Alzahrani JF - International Journal of Pharmaceutical Research and Allied Sciences JO - Int J Pharm Res Allied Sci SN - 2277-3657 Y1 - 2021 VL - 10 IS - 2 DO - 10.51847/0uEWINb8AJ SP - 129 EP - 133 N2 - Multiple sclerosis is a demyelinating autoimmune disease that commonly affects young people. Several risk factors are associated with multiple sclerosis, including low vitamin D levels. Vitamin D is essential in various regulatory processes, particularly in the immune system. Fifty years ago, vitamin D was suggested to have a role in the risk of multiple sclerosis development and relapses, which was proposed after reporting seasonal and geographic variation of multiple sclerosis incidence around the world. This literature review is intended to review the potential role of vitamin D in the risk of multiple sclerosis development or relapses. 21 articles have been selected according to the following Mesh words: Multiple sclerosis, multiple sclerosis relapse, vitamin D, cholecalciferol. Vitamin D seems to play an essential role in the immunological processes involved in multiple sclerosis, along with the indirect beneficial impact of sunlight exposure. However, up to our knowledge, there is no established consensus about the exact vitamin D’s beneficial role of among MS patients. Further multi-center randomized clinical trials are recommended to establish the preventable or therapeutic role of vitamin D in MS. UR - https://ijpras.com/article/vitamin-d-and-multiple-sclerosis-is-there-a-real-association-ajy9pkwjhz9ve86 ER -