Due to the difficult geopolitical situation, 2022 has become a turning point in many areas of trade for Russia. Many foreign manufacturers are leaving the market, giving way to domestic ones. This is especially true for the Russian pharmaceutical market, including the market for biological active supplements. In 2022, Herbalife Nutrition (USA), BAYER (Germany), ELI LILLY (USA), NOVARTIS (USA, Switzerland), GlaxoSmithKline (Great Britain), PFIZER (USA), SANOFI (France) left the Russian biological active supplement market. At the same time, the demand for biological active supplements in the country shows an extremely positive trend. In 2022, compared to the previous year, the volume of purchases of biologically active supplements increased by 19% in rubles and by 1% in packages. This article will continue detailed marketing research of the biologically active supplement market, indicate the most popular manufacturers (Evalar, Solgar, PharmaMed), give the most popular product groups (biological active supplements that affect the body as a whole, the digestive system, the nervous system), examine the dynamics of the main indicators for compared to previous years.