Today the fastest, most economical, and reasonable way of solving the problem of people’s rational nutrition is the intake of biologically active dietary supplements. This paper deals with the main trends happening in the development of the dietary supplements market. It examines the global market of nutritional supplements as well as regional markets of the USA, Canada, Germany, Russia, etc. The nomenclature of the most popular dietary supplements has been analyzed. The authors have researched the dynamics of nutritional supplements sales in terms of volume and value, assessed the average price changes of the total market and the main price categories, established the prevailing trends and their causes. It has been demonstrated that the period under study is characterized by the steady increase of dietary supplements retail sales of 6 percent a year on average. By 2019 retail sales became 3.1 times as big as they were in 2015. This process can be explained by the fact that Russian and foreign companies started promoting their innovative brands and using new highly efficient manufacturing technologies at Russian enterprises.