Deviated nasal septum (DNS) is defined as the deviation of the nasal bone, cartilage, or both from the midline of the face. DNS causes nasal blockage, watery discharge, nasal airway resistance, snoring, headache, facial pain, and cosmetic problems. DNS is the most common predisposing factor for chronic sinusitis. The present study was designed to analyze the prevalence of DNS and associated symptoms among the population ofMaharashtra state, India. Two hundred patients reporting to the school of dental sciences, Karad, Maharashtra, India were recruited based on the inclusion and exclusion criteria. The demographic data of the patients including signs and symptoms of DNS were recorded in predesigned proforma. The patients were subjected to Orthopantomogram radiographic analysis to detect the type of DNS using Carestream, CS 8100 device. The DNS was classified according to Mladinas classification and subjected to statistical analysis. Out of the 200 subjects, 132 were males and 68 were females. DNS was observed in 136 patients (80 males and 56 females). Type II DNS was the most common, followed by type III. Patients suffering from symptoms of DNS were 124, with nasal obstruction as the most common complaint followed by nasal discharge. The prevalence of DNS was more among females, and type II DNS was most common among Maharashtra’s population. Nasal obstruction was the most reported symptom. Early diagnosis and treatment of DNS in an individual, will reduce the symptoms and improve the quality of life.