The oral contraceptive pill (OCP) is a type of birth control pill that is taken orally. OCP is the world's most frequently used contraceptive method today. To estimate the prevalence of depression among hormonal contraceptive users in Taif city. The study was a cross-sectional questionnaire survey, based on a structured questionnaire that was developed by authors conducted in Taif city in the kingdom of Saudi Arabia The required sample was calculated, which is approximately 384. The prevalence of using oral contraceptive pills (OCPs) was found to be 57.5% The Beck Depression Inventory (BDI) score was calculated by adding the scores of all the items in the questionnaire. The mean scores for the BDI were found to be 14.1 ± 10.1. A BDI score of 17 or more was considered to have clinical depression, and it was found that the prevalence of depression was 37.8%. The Levels of Depression were calculated based on the total score as Normal (1-10), Mild mood disturbance (11-16), Borderline clinical depression (17-20), Moderate depression (21-30), Severe depression (31-40), Extreme depression (>40). The analysis showed that 2.4% and 4.4% demonstrated extreme and severe depression, respectively. The findings showed that females' oral contraceptive pills were the most commonly used contractive methods. About 37.8% of the females who used OCPs had demonstrated depression symptoms.