In early January 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was identified as the agent responsible for coronavirus disease 2019 (COVID-19). Recently, a high percentage of patients show a high interest in natural medicines. This is mainly due to the general feeling that natural medicines are safer than synthetic drugs. This study is designed to measure the prevalence of medical and edible plants during the (COVID-19) pandemic in Taif-Saudi Arabia. A cross-sectional study was conducted. Data was collected online using a Google forms survey. The online questionnaire was distributed to participants aged 18 years or older, living in Taif city. The data were analyzed by using IBM- SPSS version 25. In this study, we collected data from 325 participants where 76.9% of the participants were females. Considering the use of plants, 25.7% of the participants reported using Cinnamon while 20% of the participants reported using Star anise. Among the users of plants, family and friends were the main advisors of using these plants at 44.62% followed by social media at 23.69%. Moreover, 62.4 % of the participants reported using plants to protect against COVID-19 while 37.5 % reported using plants in relieving the symptoms of COVID-19. There is a significant increase in the trend of using herbs and natural products among Saudi populations, due to the COVID-19 pandemic. Cinnamon, Star Anise, and pomegranate were the main reported plants to be used by the participants.