Lobna Saad Mohammed Abd Elmeged , Khulud Mohammed Alshehri

Abstract

Medicinal plants have traditionally provided a suitable source for combating diseases of preparing new medicines. Various investigations have shown that Curcuma longa L. or turmeric is highly regarded as a universal panacea in herbal medicine with a wide spectrum of pharmacological effects. This study aimed to determine the beneficial effects of the turmeric plant on the biochemical changes in rats injected with carbon tetrachloride (CCl₄) The experiment was performed in an animal house. All animals were fed on a basal diet for 1 week before starting the experiment, then divided into 2 main groups. The first group (control negative) containing six normal rats received the basal diet only, for 28days. The second group with 18 rats was injected with (CCl₄). The second group was divided into three sub-groups, including 2 groups fed with different concentrations of (10% and 15%) turmeric, and one control positive group infected with the disease and did not feed on the experimental diet. the results showed that the total lipid of all groups was significantly more (P<0.05) when compared with control negative. Also, no significant difference was observed in liver function between the groups received 10% and 15% turmeric when compared with the control positive group.