Written by thige Rajith Neloshan Silva
Published On Issue 2 Vol 4, 2015
This study evaluated in vitro antibacterial activity and their minimum inhibitory concentration of five plants (stem of Stereospermum suaveolens,Oroxylum indicum and roots of Clitoria ternatea, whole plant of Bacopa monnieri and Alysicarpus vaginalis) used in traditional and folk medicine of Sri Lanka for treatment of various bacteria induced infectious diseases. This was performed using aqueous extracts against two gram positive [Staphylococous aureus (ATCC 25923); Bacillus cereus (ATCC 11778)]
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In the present work,the mucodhesive tablets of Glipizide were prepared by using different concentrations of Cashewnut tree gum,Aegle marmelos gum,Moringa Oleifera as a binder.The four tablet formulation was prepared by using drug and with polymer like cashew nut tree gum,Aegle marmelos gum,Moringa Oleifers gum ratio 1:0.5,1:0.75,1:1,1:1.25 by direct compression technique. Tablets were subjected to evaluation of uniformity of weight, hardness, friability, drug content uniformity, swelling studies
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Peptic ulcer disease (PUD) is one of the leading diseases throughout the world that requires a rational therapy for better therapeutic effect. Use of conventional drug regimen used as an antiulcer like; proton pump inhibitor, H2 antagonist shown incidence of relapses, side effect, and drug interaction. The use of herbal drug is the choice of drug for all kind of diseases, especially in peptic ulcer disease. This study was undertaken to evaluate the potential of anti-ulcerogenic activity of leave
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Curcuminoids, is one of the naturally occurring yellow pigments which consist of curcumin, demethoxycurcumin and bisdemethoxycurcumin, in Curcuma longa rhizome have been popularly used in traditional medicine and some extent, it is one of the active indigredients in drugs and cosmetics. In this study, natural dye curcumin was extracted from 3 differenent varieties of 10 different rhizomes. Among 3 varieties, salem variety large finger (1.92 %) and bulb(1.88%) shows higher yield of curcurmin. Whe
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UV Spectrophotometric method was developed for estimation of Frovatriptan Succinate in bulk drug and formulation. The method was validated as per ICH guidelines and found to be simple, rapid and reproducible. The method involved determination of wavelength maxima of drug in aqueous solvent and measurement of absorbance of various dilutions at corresponding wavelength. Beer’s law was obeyed in concentration range of 2 to 7 μg/ml. The developed method was applied successfully to the deter
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Asthma and COPD (Chronic Obstructive Pulmonary Disease) are the most common life threatening pulmonary disease that requires constant monitoring. Xanthine derivatives are used since a long period of time for treatment of Asthma and COPD. Doxofylline is a new generation xanthine derivative that works by inhibition of phosphodiesterase activities with no cardiovascular side effects that usually seen in case of theophylline and other xanthine derivatives due to decreased affinities towards adenosin
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Purpose: Extraction of bioactive agents from plant source to combat fungal and bacterial infections. Results: The current study encompasses in vitro antimicrobial activities of methanol, hexane, chloroform, butanol, aqueous, ethanol, ethyl acetate and dimethylsulfoxide extracts of Datura metel, Rosa indica and Citrus sinesis. Phytochemical analysis of the plant extract exhibited the presence of tannins, alkaloids, terpenoids, flavonoids and saponins. These extracts were evaluated for antimicrobi
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The present study was aimed to evaluate the antidiabetic potential of combination of punica granatum peel extract, spilanthes paniculata flower extract and selenium in streptozotocin (STZ) induced diabetes in mice. Group A was used as control and Group B was used as diabetic control (STZ, 40mg/kg for 3 days, i.p.). A placebo was given to both the group orally. Metformin (120mg/kg) was given intraperitoneally as standard drug to Group C. Ethanolic peel extract of punica granatum (EPP 600mg/kg, p.
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Written by Bahare Hajirostamlo
Published On Issue 2 Vol 4, 2015
Banana-apple juice is one of the most delicious juices. In this research, influence of temperature on the rheological behavior of banana-apple juice has been studied. The measurements were performed by capillary viscometer in 20, 40 and 60 °C. Results showed that the kinematic viscosity decreased with increasing temperature, and the temperature dependency of viscosity was found to follow the Arrhenius model. The activation energy and μ ∞ were 11.68699 Kj/g mole and 1.73 × 10-5
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Written by Ali Nematian
Published On Issue 2 Vol 4, 2015
Peptic ulcer disease (PUD) is one of the leading diseases throughout the world that requires a rational therapy for better therapeutic effect. Use of conventional drug regimen used as an antiulcer like; proton pump inhibitor, H2 antagonist shown incidence of relapses, side effect, and drug interaction. The use of herbal drug is the choice of drug for all kind of diseases, especially in peptic ulcer disease. This study was undertaken to evaluate the potential of anti-ulcerogenic activity of leave
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Written by Mohammad Zaki Shamim
Published On Issue 2 Vol 4, 2015
Background: Ginger (ZingiberOfficinale ) is well known and widely used herb especially in Asia, which contains several interesting bioactive constituents and health promoting properties. Objectives: In this view, study was conducted to analyze the inter and intra varietal differences of nutritional as well as antioxidative capacity of three varieties viz- IP 376, Suprabha and BaluaSagar of ginger. Methods: The nutritional composition was determined by the standardized procedure as described by A
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