Written by Kien-Quang Huynh
Published On Issue 4 Vol 9, 2020
Oral vaccine has been become the most effective strategy in the fight against intestinal infections because of its economy, ease, and capability on inducing responses not only systemic but also local, especially in mucosal compartments. The major obstruction to potent vaccine development is antigen dispersion and tolerance. To overcome this hindrance, we aimed to target M cells, which are the main sentinel gateway for taking up luminal antigens and initiating specific mucosal responses. In this
Read More
Written by Waleed Alhabeeb
Published On Issue 4 Vol 9, 2020
Objective: Clinical trial data on sacubitril/valsartan are important. Considering that real-world data have important clinical implications, we aimed to report the efficacy and safety of sacubitril/valsartan in patients with heart failure (HF) in Saudi Arabia.Methods: This was a pilot prospective clinical trial consisting of adult patients (≥18 years old) with HF (left ventricular ejection fraction [EF] ≤40%) who were taking angiotensin-converting enzyme inhibitors or angiotensin II recept
Read More
Written by Alanoud Abdullah Alharbi
Published On Issue 4 Vol 9, 2020
Background: Carpal tunnel syndrome is identified as an entrapment neuropathy mainly caused by compression of the median nerve when passing through the carpal tunnel of the wrist. This disease is noted a lot in society that it is shown to account for up to 90% of all neuropathies. Patients usually present with pain, numbness, and paresthesia, along with the distribution of the nerve, with variable intensity. Unfortunately, some cases may present with radiation of these symptoms affecting the whol
Read More
Written by Fayez EL Shaer
Published On Issue 4 Vol 9, 2020
A controversial echocardiographic report is usually a warning alert about hemodynamic derangement; however, tamponade is almost always a clinical diagnosis which needs supplementation of echocardiographic finding. This study presents the diagnosis of cardiac tamponade in patients with pericardial effusion through clinical and echocardiographic (ECHO) assessment. Data for 72 patients were retrieved from case notes from King Fahad Cardiac Center (KFCC) from May 2015 to May 2019. Two-dimensional, M
Read More
Written by Raghad Abdulaziz Alharbi
Published On Issue 4 Vol 9, 2020
Background: Headache is a common complaint as it is experienced by most of the general population at some stage in their lives. It accounts for 10% of the consultations of general practitioners and one-third of the referrals to neurology. One of the commonest headache disorders is migraine. Migraine can have a significant effect on the quality of life of a migraine patient. Therefore, appropriate evaluation and management are important to control such condition.Objective: To review the published
Read More
Written by Alghorayed Fiza Tariq A
Published On Issue 4 Vol 9, 2020
Background: An episiotomy is a surgical obstetric intervention that is considered when a high risk of a third- or fourth-degree laceration or a concerning fetal heart tracing necessitating an expedite vaginal delivery. Objectives:Episiotomy is an important procedure in the clinical practice of many obstetricians, therefore, in this paper, we will review the proper literature discussing indications, risk factors, complications, and management of episiotomy.Methodology: PubMed database was used fo
Read More
Written by Mark Louie S. Torres
Published On Issue 4 Vol 9, 2020
The Philippines is a multi-ethnic country with a very rich and diverse species of macrofungi. Bugkalots, a well-known ethnic group in Northern Luzon, Philippines, are believed to use various species of mushrooms as part of their daily lives. To document the ethnomycological knowledge, belief, practices, and utilization of macrofungi by the Bugkalot indigenous community in Alfonso Castañeda, Nueva Vizcaya, a survey and interview approach were used. The result of the study showed that a tot
Read More
Written by Israa Al-Ani
Published On Issue 4 Vol 9, 2020
The classical kinetic models dealt with homogeneous systems and homogeneous processes or what is called well-stirred systems. However, the thorough study of nature and the human body revealed the fractal nature of it, and the linearity between the input and output is no longer valid. System of fractal and disordered nature demanded satisfactory under dimensional constrains. In this review, some of those efforts are discussed. Fractal aspects in drug absorption from the gastrointestinal tract aft
Read More
Written by Shahd Sameer Alrowythy
Published On Issue 4 Vol 9, 2020
Background: Meniere disease is a disorder, which characteristically affects the inner ear, and may present with tinnitus, hearing loss, and vertigo. The usual course of the disease is slow and progressive and thus a lot of patients present late to primary health care centers. The family physicians need to keep in mind the association between these symptoms in order to identify this disorder and manage it properly. Objectives: We aimed to review the literature reviewing the pathophysiology of Men
Read More
Written by Bouchelaghem Sabrina
Published On Issue 4 Vol 9, 2020
Zinc oxide nanoparticles (ZnO-NPs) are common nanoparticles and widely used in many fields such as sun protection products, cosmetics, pigments, industrial coatings, plastic additives, semiconductors, textiles, and antibacterial agents. The present study was aimed to test the toxicity of ZnO-NPs on the biochemical parameters, glutathione (GSH) and catalase activity (CAT) of a single cell alternative model widely used in cellular and molecular biology: Paramecium tetraurelia. The results obtained
Read More
Written by Yasir Dakheel Alturki
Published On Issue 4 Vol 9, 2020
Background: Sexually transmitted infections are the most common communicable conditions and affect the health and lives of people worldwide. According to the World Health Organization (WHO), sexually transmitted infections are one of the four types of disease for which adults around the world most commonly seek medical help . Sexually transmitted infections can cause neonatal and fetal damages, tumors of the genital tract, and secondary infertility. A number of diagnostic strategies and tests, o
Read More
Written by Reem A. Alyoubi
Published On Issue 4 Vol 9, 2020
Introduction: Digital media and screens in their various forms are ubiquitous to modern society not only in the lives of adults but of children as well. Excessive screen time has been associated with obesity, sleep disturbance and has negatively impacted cognitive development and in some, may cause behavioral problems. Screen time has been linked to reports of headaches not only in adults but in children as well. Methodology: A cross-sectional study was conducted as an online survey distri
Read More
Written by Ahmed Saleh Al Radhwan
Published On Issue 4 Vol 9, 2020
Background: Pericarditis is inflammation of the pericardium and it is the most common pericardial disease worldwide. Although its normal function is not with such importance to the cardiac function, pericardial diseases can be dramatic for the patients and they can lead to life-threatening complications. Objective: Our aim is to review the published literature that discussed pericarditis and summarize its complications and management. Method: PubMed database was used for articles selection, and
Read More
Written by Khulud Mohammed Alshehri
Published On Issue 4 Vol 9, 2020
Medicinal plants have traditionally been used worldwide , including in Saudi Arabia. Globally, medicinal plants have received much attention because of their promising potential for use as anticancer treatments for different types of cancer, and their phytochemicals play a major role in biological reactions, such as in mediating cytotoxicity against cancer cell lines. This review highlights some important genera that belong to different naturally occurring plant families in the Al-Baha region an
Read More
Written by Hanan A. Al-Sefri
Published On Issue 4 Vol 9, 2020
Myocardial infarction (MI) is the main cause of heart failure and has a high prevalence and mortality and a great impact on social life. Naringin (Nar) and hesperidin (Hes) are citrus flavonoids, with powerful biological properties. The present study aimed to show the ameliorative effect of naringin and hesperidin and their combinations on improvement MI induced experimentally. Fifty rats were divided into five groups (ten rats each) as follow: Group 1: Healthy control group, Group 2: card
Read More
Written by Mona Othman I. Albureikan
Published On Issue 4 Vol 9, 2020
Uses of oil products increased each year which lead to soil and water contamination and many environmental problems. Bioremediation or speed up the degradation processes of these contaminants from soil and water is considered an efficient strategy for treatment. Fifteen actinomycete isolates were obtained from four oil-contaminated soil samples. All isolates were grown in liquid medium containing crude oil as carbon source. Five actinomycete isolates showed the highest growth, thus they were scr
Read More
Written by Alia M. Aldahlawi
Published On Issue 4 Vol 9, 2020
Dendritic cells (DCs) are specialized antigen-presenting cells that orchestrate the innate and adaptive immune response. The aim of this study was to prepare nanoemulsions and investigate their role in controlling DCs phenotype expression, apoptosis, and cytokine secretion. Three nanoemulsions (NEs) were produced by mixing essential oils, surfactants, and water with droplet sizes of NEs formulations in the range of 25-62nm. DCs were generated in vitro from peripheral blood mononuclear cells of h
Read More
Written by Rawan Alsehli
Published On Issue 4 Vol 9, 2020
Weight control behaviors (WCBs) are common among university students, however, not all WCBs are healthy and safe. Unhealthy WCB is common among female students especially those who suffer from excess weight. Understanding personal WCBs are important to explore because it is relevant to public health. Therefore, the main aims of the study were to explore WCB followed by female students with BMI ≥ 18.5 kg/m2 at a university located at Jeddah of Saudi Arabia, and to explore what was the main sou
Read More
Written by Ammar Y. Alshibely
Published On Issue 4 Vol 9, 2020
Background: Fractures cause problems for all human beings during their life. Supracondylar fractures are the most common pediatric elbow fracture and carry significant potential for neurovascular compromise. These fractures of the distal humerus are often problematic in terms of diagnosis, treatment, and complications. Proper care requires appropriate assessment and prompt care of patients whose fractures pose the greatest risk for long-term complications. Objectives: We aimed to review the rece
Read More
Written by Reem Abdullah Alyoubi
Published On Issue 4 Vol 9, 2020
Status epilepticus (SE) is a common medical emergency with a high morbidity rate, which can be lessened by an appropriate treatment plan. Since there is not enough structured teaching plan for the treatment of SE for post-graduate training; this research paper investigates the potential application of Kolb’s experiential learning theory (KELT) to pediatric post-graduate training for the treatment of epilepsy. The theory emphasizes the continuity of learning and the significance of experien
Read More
Written by Bashar Reada
Published On Issue 4 Vol 9, 2020
Introduction: De Quervain's tenosynovitis is characterized by inflammation and thickening of the tendons of the extensor pollicis brevis and abductor pollicis longus muscles and the synovial sheath, leading to a common cause of wrist pain that typically occurs in adults. This condition has been given several other names such as texting tenosynovitis, BlackBerry thumb, washerwoman's sprain, gamer’s thumb, teen texting tendonitis, WhatsAppitis, and radial styloid tenosynovitis, all o
Read More
IJPRAS
