Biologically Active Complex for Metabolism Normalization in People with Angioneurosis: Properties and Efficacy

The paper deals with the scientifically based composition of a new food supplement. The specialized product improves metabolism in people with nervous system disorders, its ingredients having a synergetic effect.    One tablet of the food supplement contains, mg:  Gotu Kola (fruit)  – 50 , L-glutamine acid - 50, motherwort - 25, lecithin - 25, gamma-aminobutyric acid - 25, calcium carbonate - 25, magnesium oxide - 25, choline bitartrate - 20, guarana - 16.5, ginkgo biloba (extract) - 15, hawthorn (fruit) - 15, ginseng (root) - 13, inositol - 8, L-methionine - 8, L-tyrosine - 7.5, L-phenylalanine - 7.5, L-caratin - 5, vitamin B3 - 5, B5-2.5, DNase - 4, RNase - 4, vitamin B6 - 1, vitamin B1 - 0.5, folic acid - 0.2, vitamin B12 - 00005. The authors provide biochemical characteristics of the supplement active substances to establish its functional properties and regulated quality indicators, including nutritional value, as well as a possible mechanism of metabolism normalization. The safety criteria comply with regulatory documents requirements, which have been proved by sanitary-hygienic and sanitary-toxicological studies. 

The functional properties of the specialized product and its efficacy are confirmed by conducting field trials with a representative group of patients with angioneurosis.  Taking two tablets (recommended daily dose) provides the body with the following nutrients intake (in parentheses - percentage of the recommended daily intake): vitamin B1 – 1mg (67%); Vitamin B3 - 10 mg (50%); Vitamin B5 - 5 mg (100%); Vitamin B6 - 2.0 mg (100%); Vitamin B9 - 0.4 mg (200%); vitamin B12 - 0.001 mg (30%); magnesium - 30 mg (8%), flavone glycosides (quercetin, campherol, isorhamnetin) - 2 mg (6%). The product composition and manufacturing technology have been tested and implemented at the enterprises of the company ArtLife (Tomsk), which are certified following the requirements of the international standards of the ISO 9001, 22000 series, and GMP rules. That ensures product quality and functional properties stability.