The Role of Total Disc Replacement in Degenerative Disc Degeneration, Literature Review

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Abstract

Degenerative disc degeneration (DDD) alludes to the progressive collapse of the disc to execute its function, resulting in a diminished range of motion and back inconvenience. Even though it is debilitating, the majority of people see their symptoms slowly go away without the requisite for surgery. However, numerous cases require surgical intercession, and spinal integration has been considered the gold standard for DDD in the past years. Nevertheless, spinal integration has shown to be related to a few complications. Subsequently, total disc restoration (TDR) surgery recently has been replacing spinal integration within the therapy of DDD. To review the role of TDR in DDD cases and provide a competent survey that covers the main aspects of this topic.

PubMed database was utilized for articles selection, and the following keys were utilized within the mesh ((“degenerative disc degeneration"[Mesh]) AND (“surgical management”[Mesh]) OR (“total disc replacement"[Mesh])). TDR works by mimicking the biomechanical function of an unscathed intervertebral disc, conserving physiological versatility and perhaps lowering the risk of adjacent segment degeneration as compared to lumbar fusion.


How to cite:
Vancouver
Alhifzi WS, Alqahtani FM, Luhayb WAA, Aljohani AMS, Alkhathami MMS, Taj JA, et al. The Role of Total Disc Replacement in Degenerative Disc Degeneration, Literature Review. Int J Pharm Res Allied Sci. 2021;10(1):127-35. https://doi.org/10.51847/hoJAYXW0H5
APA
Alhifzi, W. S., Alqahtani, F. M., Luhayb, W. A. A., Aljohani, A. M. S., Alkhathami, M. M. S., Taj, J. A., Alanzan, S. M., Alsaadi, M. S., Amin, A. A., Alyami, S. D. S., et al. (2021). The Role of Total Disc Replacement in Degenerative Disc Degeneration, Literature Review. International Journal of Pharmaceutical Research and Allied Sciences, 10(1), 127-135. https://doi.org/10.51847/hoJAYXW0H5