Written by Parthiban Brindha Devi
Published on Issue 1 Vol 12, 2023
The main aim of this study is to determine the bioactive compounds which have drug-like properties and has the potential to combat the spike-glycoprotein of SARS-CoV-2. The 6LXT protein of covid-19 was chosen from the protein data bank as a target protein. The compounds which are potentially capable to bind with the target were picked from the PubChem database and docked using the tool Autodock 4.2. Molecular docking of the molecules was done with the best conformations of the ligands and grid s
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Written by ElGazafey Basheer Haj Ahmed
Published on Issue 1 Vol 12, 2023
This is a cross-sectional descriptive study conducted in the River Nile State, Sudan; known with increasing morbidity of Measles. The objective is assess Measles vaccination and possibly other factors leading to abnormal high level of cases. A community-based cross-sectional, descriptive study using a questionnaire was designed to collect data, a sample of 183 was collected, vaccination cards were viewed to obtain information about vaccination status directors of Epidemiology and Immunization de
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Written by Devang Tandel
Published on Issue 1 Vol 12, 2023
To simultaneously determine quercetin and rifampicin in raw material and liquid-solid formulation, a numerical technique built on spectroscopic data associated with partial least squares (PLS) multi - variate measurement is suggested in this work. Rifampicin and quercetin spectra were captured at concentrations that fell within the 2–10 µg/ml linear range for each compound. They were used to compute 25 simulated mixtures containing 16 calibration and 9 validation sets,
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Written by Suhael Ahmed
Published on Issue 1 Vol 12, 2023
The pigmentation of oral soft tissues is predominantly an aesthetic problem because lifestyle, media, and social influences impact people's perception of beauty, which in turn affects their self-esteem as well as their relationships. The melanin pigmentation of the gingiva has become a real concern in the Gulf region, especially for younger people and females, who seek aesthetic solutions to remove the pigmentation. The pigmentation caused by melanin can be removed by surgical blades, diamon
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Written by Shatha Hallal Alziyadi
Published on Issue 1 Vol 12, 2023
The oral contraceptive pill (OCP) is a type of birth control pill that is taken orally. OCP is the world's most frequently used contraceptive method today. To estimate the prevalence of depression among hormonal contraceptive users in Taif city. The study was a cross-sectional questionnaire survey, based on a structured questionnaire that was developed by authors conducted in Taif city in the kingdom of Saudi Arabia The required sample was calculated, which is approximately 384. The prevalen
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Written by Girish Suragimath
Published on Issue 1 Vol 12, 2023
Mishri is a form of smokeless tobacco used as a dentifrice in rural areas of central India. Mishri is applied to teeth and gums to clean the oral cavity. Mishri use has ill effects on oral health and periodontal tissues. T he present study assessed the ill effect of mishri application periodontal tissues, and its correlation to the duration of use. A total of 300 subjects who used mishri as a dentifrice were considered. The enrolled subjects were categorized into three subgroups depending on the
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Written by Anshoo Agarwal
Published on Issue 1 Vol 12, 2023
Gallbladder benign diseases are common and usually cured without further consequences. Some benign illnesses increase the chance of cancer development significantly, whereas others resemble malignant disorders. The biomarkers discussed thus far are among the most extensively researched concerning the different diseases of GBC. Patients with gallbladder cancer are usually diagnosed in later stages when conventional treatments are ineffective. The lack of responsiveness of advanced instances of GB
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Written by Erumalla Venkata Nagaraju
Published on Issue 1 Vol 12, 2023
The increasing population has prompted scientists to explore novel technologies to manage health concerns. Multidrug therapies occupy a prominent position in disease management. Among all the pharmaceuticals, Disease-Modifying Anti-Rheumatic Drugs (DMARDs) captivated global researchers to accomplish the needs of Rheumatoid Arthritis (RA) management. Researchers have documented side effects associated with medications in addition to the therapeutic effects. The issue of infertility is one of the
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Written by Deniz Al-Tawalbeh
Published on Issue 1 Vol 12, 2023
Male infertility accounts for about 8 – 14 % of couples worldwide with high dependence on conventional and alternative medicine for treatment. Herbal medicine may be used to treat sperm-related problems, enhance libido or improve hormone levels thus; it is crucial to report the herbal medicine being used by patients in Jordan and highlight their mechanism of action. We searched available ethnopharmacological articles in Jordan where plant use for male infertility was mentioned, collect her
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Written by Satyam Baghel
Published on Issue 1 Vol 12, 2023
In this ever-growing world, it is crucial to improve upon the formulations in terms of potency, patient acceptability, fewer side effects, and quicker relief. Due to these requirements, the market is flooded with various combination dosage forms, with a constant increase in number. Paracetamol is a commonly used non-steroidal anti-inflammatory drug (NSAID) that has antipyretic and analgesic action. This drug is available in a wide range of combinations. It acts by inhibiting the production of pr
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Written by Hosam Zakaria Mohamed
Published on Issue 1 Vol 12, 2023
Disorders of the cauda equina are etiologically and physically connected to the neuromuscular system in the spinal cord. A thorough history and neurological examination are necessary for clinical recognition of a cauda equina-affecting condition, and to make a rapid diagnosis, the selection and interpretation of relevant neuroimaging investigations, neurophysiologic testing, and laboratory tests are necessary. The diagnosis and treatment of Cauda Equina Syndrome (CES) are difficult. It could app
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Written by Ahamd Elssayed
Published on Issue 1 Vol 12, 2023
The most prevalent non-traumatic debilitating illness affecting young individuals is multiple sclerosis (MS) (2). Both industrialized and emerging nations are seeing an increase in the incidence and prevalence of MS, whose underlying etiology is still unknown. In addition to some well-known environmental variables, such as vitamin D or ultraviolet B light (UVB) exposure, Epstein-Barr virus (EBV) infection, obesity, and smoking, MS is a complicated illness with sever
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Written by Mohammed Mady
Published on Issue 1 Vol 12, 2023
Pediatric dentistry includes key subspecialties that deal with the diagnosis and treatment of dental abnormalities. These diseases range from having no teeth at all (anodontia) to having more teeth than one would typically have (hyperdontia). When referring to missing or absent teeth, some people may use the term "agenesis," which is the inability of all or a portion of an organ to form during embryonic growth. Some kinds of dental agenesis can be catastrophic and debilitating, resulti
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Written by Saeed Ghurmallah AlZahrani
Published on Issue 1 Vol 12, 2023
The Healthy School (or Health-Promoting School as a term used by WHO and other countries) is a whole-school approach to promoting health in a school setting. Healthy Schools and Health-Promoting Schools frameworks extend around the globe are important strategies that provide opportunities to improve the health of children and adolescents and to tackle health inequalities in the population. Two decades since the Healthy Schools framework was advocated in Saudi Arabia. This paper sets out to revie
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Written by Elgeili Yousif
Published on Issue 1 Vol 12, 2023
This work aimed to standardize and state” the insufficiencies outlined and variation in image quality, among some hospitals in Sudan for a common in specific radiologic examinations. A subjective evaluation of 1,103 image reproductions from “363 special radiologic procedures including Intravenous Urography (IVU), Hysterosalpingography (HSG), GIT barium studies” and Micturating Cystourethrography (MCUG), and the Entrance Air Surface Kerma (ESAK) values recorded for each procedur
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Written by Rawan Samy Abou-assy
Published on Issue 1 Vol 12, 2023
In recent years, carbapenem-resistant Enterobacteriaceae (CRE) has expanded quickly throughout the world, posing a serious threat to public health. They are also very difficult to treat and are associated with a high fatality rate. The class of antimicrobials known as carbapenems is regarded as the most trustworthy and last line of defense. It is possible to distinguish between CRE resistance mechanisms that produce carbapenemase enzymes and those that do not. The three classes of β-lactama
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Written by Hanan M. Alharbi
Published on Issue 1 Vol 12, 2023
Zein has been used in several pharmaceutical applications because of its unique composition. It is an amphiphilic molecule that is biodegradable, biocompatible, and has adhesive, matrix-forming, and film-coating properties, making it a promising pharmaceutical excipient. Zein-based formulations have been investigated in tablet-coating, nanoparticulate delivery systems, and controlled-release formulations. However, to date, very few studies have been performed on the inclusion of zein in solid di
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Written by Florica Voiţă-Mekereş
Published on Issue 1 Vol 12, 2023
One of the most vital organs in the body is the nervous system. Damage to the nervous system may lead to a variety of issues and illnesses in people, and each year, both the affected person and society incur significant financial, human-life, and spiritual expenses as a result. Although the activity in the field of nerve repair and regeneration is growing rapidly, until now, nerve repair is not done completely. A chain of events, including inflammation, elevated oxidative stress, and the progres
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Written by Florica Voiţă-Mekereş
Published on Issue 1 Vol 12, 2023
One of the worst developmental abnormalities, autism spectrum disorder, is often identified before the age of three. All forms of autism impair people's capacity to communicate with others, despite the fact that each person's symptoms and degree of severity vary. Despite the fact that there is no known cure for autism, children who receive prompt and serious treatment see significant improvements in their quality of life. The deficiencies in social functioning seen in individuals with au
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Written by Tiberia Ioana Ilias
Published on Issue 1 Vol 12, 2023
Leptin is derived from the Greek word leptose, which means thinness, and was discovered in 1994 by isolating the obesity gene. This substance is a protein hormone with a helical structure similar to cytokines, which is mainly synthesized and released by the subcutaneous fat cells in a constant pulsating manner with a peak secretion near midnight. A key factor in controlling energy and metabolism, which has an impact on body weight, is leptin. Leptin, which is produced by the obesity gene, has be
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