Written by Karthikeyan Ramadoss
Published On Issue 4 Vol 12, 2023
The major topic of this review study involves the connection between particular scientific, legal, and regulatory elements of pharmaceutical crystal forms. By referring to current scientific advancements in this area, the article provides an examination of pharmaceutical co-crystals as patentable inventions. The following few potential business benefits of pharmaceutical co-crystals and the other recent court rulings concerning important problems are compiled. The regulatory status of co-crystal
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Written by Mohammed A. Almatrafi
Published On Issue 4 Vol 12, 2023
Screen time in young children is associated with emotional, behavioral, and sleep problems that impact children's growth and development. Data regarding television (TV) screen time among preschool-age children in Saudi Arabia are scarce. We aimed to assess the relationship between parents' sociodemographics, sedentary behaviors, and TV screen time among preschool-age children in Saudi Arabia. An online-based cross-sectional study using a previously validated survey was conducted through
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Written by Vennamaneni Deepika Rao
Published On Issue 4 Vol 12, 2023
The study was undertaken to determine the sequel of two training methods, i.e., Weight and Circuit training on specified physical components for Sprinters of Hyderabad. Forty-five inter-collegiate Male Sprinters aged 18 to 22 years were taken as subjects and divided into weight training group– G-I (n=15), circuit training group – G-II (n=15), and control group G- III (n=15). Both experimental Groups were given specific training, and G-III, which represented control, was not given any
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Written by Aishwarya Dange
Published On Issue 4 Vol 12, 2023
Rhus succedanea L., a tree belonging to the Anacardiaceae family is also known as Kuntze. Traditional systems of medicine have used Rhus succedanea L. to treat a variety of ailments like infections, dysentery, nose and gum bleeding, cough, tuberculosis, fever, and asthma. Several phytoconstituents such as robustaflavone, volkensiflavone, agathisflavone, succedanea flavanone, and rhusflavone have been isolated from this plant species responsible for several pharmacological actions. The anti-infla
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Written by Ahmed Alsolami
Published On Issue 4 Vol 12, 2023
Irritable Bowel Syndrome (IBS) continues to be a pervasive gastrointestinal disorder affecting millions worldwide, imposing a significant burden on healthcare systems and impacting the quality of life for those afflicted. This review aims to provide a comprehensive overview of the current understanding of IBS by exploring its epidemiology, detailing its complex pathophysiology, and examining contemporary therapeutic approaches. The paper discusses the prevalence and demographic factors associate
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Written by Nessrin Ghazi Alabdallat
Published On Issue 4 Vol 12, 2023
Hemoglobinopathies are inherited diseases of hemoglobin synthesis arising from mutations and/or deletions of one or more of the globin genes resulting in the production of abnormal hemoglobin molecules and subsequently reduced synthesis of normal alpha and beta globin chains in Hemoglobin molecules. In this study, we attempted to assess the distribution of hemoglobinopathies in Saudi Premarital couples planning to marry and applying for a marriage license in Al Majmaah region and attending the p
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Written by Nisha Joseph
Published On Issue 4 Vol 12, 2023
Diabetes mellitus is a complicated health disorder that pushes human life into misery. Oral hypoglycemic agents are not effective for a complete cure, and it has side effects, too. Herbal remedies have long been used to treat diabetes and are widely accepted due to reduced side effects. Aqueous extracts made from dried leaves of Azadirachta indica, whole plant parts of Biophytum sensitivum, aerial roots of Cocos nucifera, and dried leaves of Passiflora edulis were used in this work to examine th
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Written by Patel Priteshkumar
Published On Issue 4 Vol 12, 2023
The chemical constituents quinazolinone and piperazine hold significant importance in the realm of organic compounds due to their diverse range of biological and therapeutic attributes. In an effort to investigate the possible uses of these molecules, a team of scientists synthesized a unique set of chemical substances that combined piperazine and quinazolinone structures. This research involved a comprehensive investigation into the antimicrobial properties of a set of derivatives bearing the c
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Written by Bushra Abdulkarim Moharram
Published On Issue 4 Vol 12, 2023
Diabetes Mellitus (DM) is among the most common metabolic disorders worldwide. Leaves of Capparis cartilaginea are used in folk medicine to treat diabetes in parts of Yemen. The current study aimed to investigate the antioxidant and antidiabetic effects of C. cartilaginea leaf extract. The antioxidant activity of the extract was determined using a 2.2 – diphenyl -1- picrylhydrazyl (DPPH) free radical scavenging assay. Experimental diabetes was induced in rats by alloxan (200 mg/kg),
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Written by Fatemah O. Kamel
Published On Issue 4 Vol 12, 2023
Epilepsy is one of the most prevalent chronic neurological illnesses. Presently, the provision of symptomatic medicine is the treatment method for epilepsy. The majority of patients can attain seizure independence during the first two medication trials. Therefore, pharmaco-resistant individuals are those who cannot get an adequate therapeutic response. However, the range of efficacy, safety, and tolerability, the diversity of seizures and epilepsies, the frequency of comorbidity, and tolerance a
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Written by Salah Uddin
Published On Issue 4 Vol 12, 2023
Water is a very precious gift of nature. Groundwater is the main source of water for horticulture and human drinking purposes in many areas where alternating methods are not available such as rivers, lakes. etc. So Ground water is the main source for sustaining life. To analyze the ground water to attain the decision whether the water useful for drinking purposes or not. Six sampling sites were chosen to collect the groundwater samples. The specimen is collected in the morning hours from the sel
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Written by Shroug Farrash
Published On Issue 4 Vol 12, 2023
Obesity and diabetes, one of the most common diseases can cause a several complications. In diabetic patient with type 2 we mainly use an oral medication with varies mechanism of action such as: GLP-1 medication. To look at semaglutide's (a new glucagon-like peptide receptor agonist; GLP-1 RA) effectiveness in treating individuals with diabetes and obesity. We followed the guidelines of the PRISMA checklist for conducting this study. On 23rd October 2022, we run a systematic search “&l
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Written by Bandar Alsaif
Published On Issue 4 Vol 12, 2023
The COVID-19 pandemic was found to be associated with work stress among workers in healthcare organizations, and it may have increased the risk of experiencing workplace incivility. It is a form of interpersonal mistreatment and becoming a huge concern due to its negative implications both on employees’ well-being and organizations’ efficiency. A descriptive quantitative research design was employed to investigate the experiences of workplace incivility among nursing professionals an
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Written by Raneem K AlMusaed
Published On Issue 4 Vol 12, 2023
Nigella sativa (black seed), Syzygium aromaticum (clove), and Commiphora myrrha (myrrh) are examples of medicinal plants that have gained popularity in the last decades due to their high contents of phytochemical constituents and consequently to their potent biological activities. Different extracts of the aforementioned medicinal plants were prepared, using organic solvents acetone and methanol, as well as a water extract; they were evaluated separately for their antibacterial activities agains
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Written by Li Liu
Published On Issue 4 Vol 12, 2023
Stroke is a kind of sudden onset of cerebral circulatory disorders with transient or permanent symptoms and signs of brain dysfunction clinically, it has a high incidence rate and a high mortality rate and is one of the severe cerebrovascular diseases that threaten human life and disability seriously and bring the heavy economic burden to patients and their families, there was no ideal treatment for it. Mesenchymal stem cells (MSCs) are a type of primitive undifferentiated cells with multi-direc
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Written by Kavita Gour
Published On Issue 4 Vol 12, 2023
Green synthesis of nanoparticles has evolved as an ecologically friendly and sustainable method for producing nanoparticles using natural sources like botanical extracts. Withania somnifera, commonly known as ashwagandha, is a medicinal plant known for its diverse therapeutic properties. This work focuses on the green synthesis, characterization, and applications of selenium nanoparticles (SeNPs). The ecologically sound production of selenium nanoparticles using extracts of Withania somnifera ex
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