Written by Rajesh K. Patel
Published On Issue 3 Vol 9, 2020
A Simple, rapid, specific, accurate, economical and precise UV spectrophotometric and RP-HPLC methods (in accordance with ICH guidelines) were developed and validated for determination of Nortriptyline hydrochloride and Pregabalin in tablet dosage form. The first method was based on Q - absorbance ratio, and absorbances of both drugs were determined at 239 nm (λmax of Nortriptyline Hydrochloride) and 235 nm (Iso-absorptive Point) when dissolved in methanol. It is found that Pregabalin doe
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Written by Kudryashov Leonid
Published On Issue 3 Vol 9, 2020
The article aims to develop the technology of the production of herbal protein isolates with 41% protein concentration by enzymatic hydrolysis. The technology includes preparing a hydro module from shredded lupine seeds and water in proportion 1:10, hydrolysis of starch with alpha-amylase and glucoamylase, centrifugation, autoclaving of the obtained centrifugate at the temperature of 120-130º С and the pressure of 6х105 Pa for 5-6 hours, cooling it to the temperature of 36º С and hydro
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Written by Carlo Maretti
Published On Issue 3 Vol 9, 2020
Introduction: Efficacy evaluation of a new treatment, improving the symptoms of Peyronie’s disease (PD) in patients with a curvature deformity < 30° and with an onset of symptoms of at least 6 months before the treatment. We investigated the effects of Transfer Capacitive Resistive Energy (TCARE) therapy accompanied by hydroelectrophoresis (HEP), a new electromotive system, for the transcutaneous delivery of Verapamil in men with PD. Materials and Methods: Sixty-one patients affecte
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Written by Hanadi Sabban
Published On Issue 3 Vol 9, 2020
Dentists must understand the role of maxillary sinus diseases and their relationship to teeth and supporting structures. The most maxillary sinus disease is Odontogenic maxillary sinusitis. Cone-beam computed tomography (CBCT) is the imaging choice in dental practice to evaluate maxillary sinuses and maxillofacial structures. Maxillary sinuses carry a variation of mucosal thickening. If the mucosa of maxillary sinuses exceeds more than 2 mm, it indicates the possibility of infection in the maxil
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Written by Ulfat M. Omar
Published On Issue 3 Vol 9, 2020
Tea is one of the most widely consumed beverages in the world and is recognized as having numerous beneficial health effects due to its phenolic content. The current study aimed to evaluate and compare the phenolic and flavonoid content of two forms of Twining English Breakfast Tea: tea bags (TBs) and opened tea bags (OTBs). The antioxidant activity was also assessed using DPPH, FRAP, and CUPRAC assays. The results obtained revealed that the OTB infusion exhibited significantly higher phenolic a
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Written by Zabihollah Mohammad Alipour
Published On Issue 3 Vol 9, 2020
To investigate the yield of different cultivars of canola and selection of cultivars with high production and appropriate to cold areas of Lorestan Province, an experiment was carried out in a complete randomized block design with 13 cultivars and 4 lines and three replications in Biranshahr area of Khorramabad city in the crop year of 2017-2018. The results of the analysis of variance showed that plant height, number of siliques, number of seeds per silique, number of secondary branches, pod le
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Written by Eman S. Alamri
Published On Issue 3 Vol 9, 2020
Objective: This study is aimed at assessing the nutritional value of the food consumed during school meal breaks by Saudi schoolchildren in a healthy school and comparing it with that in another school (a normal school). Methods: A total of 260 schoolchildren from two elementary schools in Tabuk were recruited in the present study. The children were observed at school meal time, and all food consumed by them was recorded by a trained research assistant. The portion size of the consumed food was
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Written by Kudryashov Leonid
Published On Issue 3 Vol 9, 2020
This article was aimed to develop an antioxidant meat paste using a protein supplement from lupine seeds enriched with selenium and obtained by enzymatic hydrolysis. It was established that the content of selenium, flavonoids, and antioxidant activity in lupine seeds when they are germinated in a solution of sodium selenite with the use of red light after three days is significantly higher. Therefore, technology and recipe of meat paste using a protein preparation has been developed. It has been
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Written by Saat N. Z. M.
Published On Issue 3 Vol 9, 2020
Poor sleep quality among university students is a rising concern as it affects their well-being. Studies have shown an association between physical activity and sleep quality; however, studies in a local context focussing on health sciences undergraduate students are scarce. Thus, a cross-sectional study aiming to assess the prevalence of poor-quality sleep and its association with physical activity was conducted among health sciences students in Kuala Lumpur. A total of 90 undergraduate student
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Written by Pozdnyakova Olga Georgievna
Published On Issue 3 Vol 9, 2020
The clinical trial aimed to study the effectiveness of a dietary supplement for respiratory system diseases therapy. Children underwent treatment during both acute and convalescent stages, and in addition to their primary treatment received the plant-based dietary supplement. The new plant-based dietary supplement with ingredients possessing synergetic properties was developed to supplement the normal diet and help correct metabolism disorders in the case of respiratory diseases. The ingredients
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Written by Natalia Borodina
Published On Issue 3 Vol 9, 2020
Determination of the mineral composition is important for further study and standardization of the dried branches of the species from the Salix (willow) family genus and extracts from the plant material. The study aimed to determine the qualitative and quantitative content of macro- and microelements in some representatives of the Salix spp. growing in Ukraine in comparison with soils and extracts of plant material. The elemental composition of the branches of Salix cinerea L., S. incana Schrank
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Written by Othman Majed Alothman
Published On Issue 3 Vol 9, 2020
Background: Depression is a common mental disorder in adults, and the World Health Organization (WHO) has ranked it as the fourth leading cause of disability worldwide. Doctors are not immune to the disorder; in fact, they have a higher risk than the general population, which affects the physician’s life and compromises the quality of the health services. In Saudi Arabia, resident doctors’ mental health is under-recognized, and more studies need to be conducted to fill this gap. Obje
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Written by Muhammad Ali Rajput
Published On Issue 3 Vol 9, 2020
Nelumbo nucifera fruit (NNF) is frequently used for the treatment of many diseases in Asian countries without proper scientific evidence of its safety. The purpose of this study was to determine the toxicological effects of NNF. Toxicity study was conducted on 28 male Wister rats weighing 180-230 g that were allocated equally to 4 treatment groups; a control and 3 test groups. Parameters assessed were clinical signs, body weight, hematology, blood biochemistry and histopathology after administra
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Written by Faisal Ali Al Jabr
Published On Issue 3 Vol 9, 2020
Background: Reactive oxygen species (ROS) may cause extensive tissue damages in various disease conditions. It may also induce an irreversible structural and/or functional modification of proteins. Flavonoids and their derivatives are the largest group in plant polyphenols that are known to have an antioxidant effect. The aim of the present study is to evaluate the antioxidant effects of red or white cabbage on bovine serum albumin (BSA). Methods: Fresh leaves of red or white cabbage were washed
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Written by Pouya Toghyani
Published On Issue 3 Vol 9, 2020
To compare the effect of eucalyptus extract and formaldehyde gas on the hatchability, survival rate, and microbial load of embryos and biological biomarkers of embryos in the fertile eggs of broiler chicken, 120 fertile eggs were divided into four groups (each group contained 30 eggs). The studied groups included the first and second groups in which eucalyptus extract at concentrations of respectively 1.100 and 1.200 was used as a disinfectant, the third group in which formaldehyde gas was used
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Written by Dalia A. Abdulla
Published On Issue 3 Vol 9, 2020
Polypharmacy, which is the practice of prescribing five or more medicines to the same patient is associated with many problems like adverse drug reactions and poor adherence to therapy and can be harmful. Recently, the term deprescribing is used to describe the systematic process of identifying and discontinuing medicines in situations in which potential or existing harms outweigh potential or existing benefits for the seek of individual patient care goals and preferences. Many studies assessed
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Written by Lyudmila Makartseva
Published On Issue 3 Vol 9, 2020
The effect of the stay of 6-months-old male Wistar rats under the influence of constant lighting on the daily dynamics of some biochemical parameters was studied. Male Wistar albino rats at the age of 6 months were divided into 2 groups. The rats from the Group I were housed under a fixed illumination, L:D 14:10 (±180 lux, respectively; 8:00 AM lights on) (unless mentioned otherwise) in a temperature-controlled environment with ad libitum access to tap water and food (rat chow). Animals o
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Written by A.G. Pogorelov
Published On Issue 3 Vol 9, 2020
Microporous materials can provide interesting tools for different goals from bioimaging to the delivery of bioactive molecules. In this study, the procedure based on cryo-approaches was designed to formulate the nanoparticles of natural clinoptilolite from the Zeolites mineral family. Applying scanning electron microscopy, clinoptilolite samples were imaged. After aging in the ethanol solution of phosphatidylcholine (lecithin), nanoparticles were encapsulated in the lecithin envelope. The adsorp
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Written by Lateef Mohiuddin Khan
Published On Issue 3 Vol 9, 2020
Background: Nigella sativa (NS) has antioxidant and neuroprotective effects. Its concurrent use with AEDs could be a promising health strategy to prevent the damaging effect on neuronal cells during the episodes of seizures in addition to enhancing therapeutic effects and diminishing the adverse drug reactions of AEDs. Purpose: To provide the pragmatic perception of utilizing TQ as an adjuvant in antiepileptic therapies to potentiate their actions. Methods: The study utilizes systematic reviews
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Written by Syed Ibrahim
Published On Issue 3 Vol 9, 2020
The purpose of the study was to examine the efficacy of 8 weeks of protein supplementation plus hyper-caloric intake and resistance training on hypertrophy, hormones, and energy components of underweight males. One hundred sixty-seven underweight males from Dhahran region aged 18 to 20 years with BMI of less than 18.5 Kg/m2 were divided into protein supplementation with hyper-caloric intake and resistance training group 1 (G-1, n =21), the resistance training group 2 (G-2, n=48), protein supplem
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Written by Fayez EL Shaer
Published On Issue 3 Vol 9, 2020
Sarcoid Heart Disease (SHD), often misdiagnosed as tuberculosis is a potentially life-threatening condition. Cardiac manifestation of sarcoidosis is a challenging clinical condition as it is associated with pericarditis, heart block, ventricular arrhythmias, valve dysfunction, ventricular aneurysm, sudden cardiac death, and heart failure. This study presents a case of a syncopal attack due to complete heart block, which is the first indication of SHD. The study has also presented a literature re
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Written by Muhammad Atteya
Published On Issue 3 Vol 9, 2020
Objective: There are four currently motor features characterizing Parkinson's disease (PD). These include rigidity of muscles, bradykinesia, tremors at rest, and instability of posture. Along the course of PD, the impairment of motor functions is commonly preceded by nonmotor symptoms (NMS) such as olfactory deficit, difficult swallowing (dysphagia), drooling (sialorrhea), constipation, urinary bladder dysfunction, depression, and sleep disorder. It was suggested that the enteric nervous sys
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Written by Mostafa Al-Shamiri
Published On Issue 3 Vol 9, 2020
Patients with atrial fibrillation (AF) are at a higher risk of thrombotic stroke. Therefore treatment with an oral anticoagulant (OAC) has been proven to prevent stroke, however, the bleeding side effect of OAC is the concern for both physicians and patients. Patients’ knowledge of the stroke and bleeding related to AF is lacking in Saudi Arabia. We conducted this study to assess the knowledge of patients on AF related to stroke and bleeding from OAC. Method: this is a cross-sectional stud
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Written by Fayez Saud Alreshidi
Published On Issue 3 Vol 9, 2020
Background: As adjusting the treatment dose for hypothyroidism based on several factors requiring continuous rigorous assessment, the current study aimed to assess of Saudi people’s knowledge about hypothyroidism treatment usage. Methodology: This is a cross-sectional study, piloted in Hail Region, Northern Saudi Arabia. In this study, 900 respondents were randomly involved in the study irrespective of their age, sex, or other demographical characteristics. Results: The present study inves
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Written by Reema S. AlHammad
Published On Issue 3 Vol 9, 2020
Background: Any subject that knows about Cardiopulmonary Resuscitation (CPR) will be able to save many lives. So imagine how vital would be the role of CPR in a profession specially that of firemen. Logically, all firemen should have the knowledge and awareness regarding CPR, but is that really the case? Objective: Assessing the knowledge level, causes of poor knowledge of CPR and the attitude towards CPR training courses among firemen in Riyadh, Saudi Arabia. Methodology: This was a cross-secti
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